CD157 (BST1) ELISA Kits

ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human CD157 (BST1) can be quantified in various samples, including plasma, serum, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated.... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human CD157 (BST1) can be quantified in various samples, including plasma, serum, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated.... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human CD157 (BST1) can be quantified in various samples, including plasma, serum, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human CD157 (BST1) can be quantified in various samples, including plasma, serum, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits are ready-to-use and quality tested for sensitivity, specificity, precision and lot-to-lot consistency.

靶标信息

CD157, also known as Bone Marrow Stromal Cell Antigen 1 (BST1), is a pleiotropic ectoenzyme and glycosylphosphatidylinositol-anchored molecule that functions both as an enzyme and a receptor. Similar to CD38, CD157 is involved in the metabolism of NAD+, which may play a role in regulating intracellular Ca2+ levels. As an enzyme, CD157 is also referred to as ADP-ribosyl cyclase 2 and DAMP-1, and it facilitates pre-B cell growth. As a receptor, CD157 is thought to initiate a signal transduction cascade upon binding to its putative ligand, leading to the phosphorylation of cytoplasmic proteins, including focal adhesion kinase (FAK). While the mechanism and functional significance of CD157-initiated signal transduction are not fully characterized, its role in cellular signaling is evident. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis, suggesting a link to polyclonal B cell abnormalities observed in the disease. This overexpression in the stromal cell population may contribute to the pathophysiology of rheumatoid arthritis, highlighting the importance of CD157/BST1 in both normal immune function and disease states.

同义词

114/A10; A530073F09; ADP-ribosyl cyclase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; antigen BP3; Bone marrow stromal antigen 1; bone marrow stromal cell antigen 1; Bp3; Bp-3; BP-3 alloantigen; Bst1; BST-1; Bsta1; cADPr hydrolase 2; CD157; CD157 antigen; Cyclic ADP-ribose hydrolase 2; leukocyte antigen 65; Ly65; Ly-65; NAD(+) nucleosidase; NAD+ nucleosidase

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Invitrogen

Human ADP-Ribosyl Cyclase 2 ELISA Kit

Invitrogen

Human ADP-Ribosyl Cyclase 2 ELISA Kit

灵敏度 0.06 ng/mL

测定范围 0.06-12.50 ng/mL

样品容量

Serum

50 µL

Plasma

50 µL

Supernatant

50 µL

总时间

4 hr 45 min

(1 hr 20 min hands-on)

价格

货号 EH15RB

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